I installed the new NOS distributor I got from forum member chevy2inreno on the 250 6-banger on Sunday. Checked initial timing on the old one, was set at about 8 degrees BTDC. Spec is 4 BTDC, but I've heard from old GM mechanics that timing should be advanced to just before pinging starts on regular gas with this motor.
So installed the new distributor and set initial timing at the same 8 BTDC. Drove the truck to work today- HOLY CRAP! what a difference. Way more acceleration, should have done this a long time ago, but I though the old distributor was OK.
Think I've got the Rochester B and the spark timing dialed in pretty good now.