Engine Build Ideas

[ol'blu72]

So I think my engine build is actually going to happen. Well I should say rebuild. I saved almost enough money and can con the wife out of the rest lol. I have a small water leak comming from the back of the drivers head. I also have knocking noise comming from the belhousing area. Im told this is probably a cracked flexplate.
Here is the current stats. Its a 72 blazer that is almost totally stock besides the Edelbrock1406 and Edelbrock intake. 32in tires and (i believe) 3.75 gears.

Where I want to go. I want to find a good combination for torque and good street manners. So this is what im thinking

Vortecs
Comp extreme 4X4 cam
performer air gap intake
new Edel 600cfm
CR?

Im looking for any problems with this setup, better ways to go, where I need the CR to be, and any other helpful info. This will be my first build so I am working the learning curve. Here are some of my stupid questions.

Can I go to a roller cam?
I caught some reading about cylinder quench. Where should this be set at?