I own a commercial version of EFI Live, and have always tuned my own stuff on the street and on the track.
The Blazer however, has a Megasquirt ecu on it, and does not need to be "flashed" in the traditional sense. I can tweak fueling, timing, boost values on the fly and it changes immediately.
Just a friendly heads up, but there is no such thing as "predetonation". I think you're combining two different things.....pre-ignition, and detonation.
http://en.wikipedia.org/wiki/Engine_knocking
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1972 2wd K/5 Blazer Turbocharged 370 LSx - 941 rwhp / 1093 rwtq
1969 Chevy K-10 L33 5.3 / 4L80E / NP241 / 4" lift
1964 Buick Skylark Twin TURBO 383 LS pro-touring project
2014 VW Passat TDI - Daily Driver
Turbo diesel
2015 Sierra Denali HD Duramax Turbo diesel
2016 Ford Explorer Sport - Twin Turbskis
2017 Polaris RZR Turbo
2014 Nor-Tech Center Console - Twin Supercharged Outboards
TURBO ALL THE THINGS!!